Huzzah Creek (locally /ˈhuːzɑː/) is a 35.8-mile-long (57.6 km)[3] clear-flowing stream in the southern part of the U.S. state of Missouri.

[5] The Huzzah's headwaters are in the Mark Twain National Forest in northern Reynolds County.

It flows northward through the Missouri Ozarks, roughly paralleling the course of Courtois Creek to its east, until it enters the Meramec River shortly after passing under the Crawford County Highway E bridge.

Along its course it flows through the Dillard Mill State Historic Site and, near its confluence with the Meramec, the 6,225-acre (2,519 ha) Huzzah Conservation Area.

It is surrounded by limestone bluffs and stands of native pine, oak, and hickory trees; and at normal water levels it has no sections of difficulty greater than grades I and II.