1T0P3385n/aENSG00000076662n/aP32942n/aNM_001395375NM_001395376n/aNP_001307534NP_001307535NP_001307537NP_002153n/aIntercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50), is a protein that in humans is encoded by the ICAM3 gene.

[3] The protein is constitutively expressed on the surface of leukocytes, which are also called white blood cells and are part of the immune system.

[6][9][10] ICAM3 is a 110–160 kDa protein that belongs to the intercellular adhesion molecule (ICAM) family.

[10] These altered proteins allow macrophages to specifically target and bind apoptotic cells.

[11] ICAM3 has been shown to interact with activated ERM proteins, including ezrin (EZR) and moesin, in T cells.

[15] This article incorporates text from the United States National Library of Medicine, which is in the public domain.