Note that the β7 subunit can bind with other integrin α chains, such as α4 (CD49d).

[8] A subset of dendritic cells in the gut mucosa and mesenteric lymph nodes, known as CD103 dendritic cells, also expresses this marker.

[9] It is useful in identifying hairy cell leukemia which is positive for this marker in contrast to most other hematologic malignancies which are negative for CD103 except for hairy cell leukemia variant, a fraction of splenic marginal zone lymphomas, and enteropathy-associated T cell lymphoma.

[10] The chief ligand for αEβ7 is E-cadherin, a cellular adhesion molecule (CAM) found on epithelial cells.

[13] Tregs are important for decreasing the immune response and appear to play a crucial role in the prevention of autoimmune diseases.