Nilsen began a YouTube channel with the name Missglamorazzi[2] on October 23, 2009, because she wanted to share her feeling of confidence with other people and push herself to overcome her fear of public speaking.

[7][8] In March 2016, Nilsen was named one of the United Nations Change Ambassadors to the intergovernmental organization along with six other female YouTube creators.

The UN Change Ambassadors focused on the global fight for gender equality, one of the UN's 17 Sustainable Development Goals established that year.

[9] In mid-2016, Nilsen was named one of the SuperSoul100, Oprah Winfrey and OWN's list of innovators and visionaries aligned on a mission to move humanity forward.

The campaign encouraged participants to run product drives for unopened tampons, pads, and panty liners that were then donated to local homeless shelters.

"With a powerful social presence, Ingrid has used technology for the better and built a platform and voice to advocate for equality," said Abbe Land, Executive Director and CEO of The Trevor Project.

Nilsen led #TheirStory campaign which asked LGBTQ+ members and their allies to share stories about inspirational figures via online videos.