365516403ENSG00000091409ENSMUSG00000027111P23229Q61739NM_001394928NM_001277970NM_008397NP_000201NP_001073286NP_001303235NP_001352458NP_001352459NP_001264899NP_032423NP_001393187Integrin alpha-6 is a protein that in humans is encoded by the ITGA6 gene.
A given chain may combine with multiple partners resulting in different integrins.
Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
Two transcript variants encoding different isoforms have been found for this gene.
[5] Specific loss of this integrin chain in the intestinal epithelium, and thus of their hemidesmosomes, induces long-standing colitis and infiltrating adenocarcinomas.