Isaiah 16 is the sixteenth chapter of the Book of Isaiah in the Hebrew Bible or the Old Testament of the Christian Bible.

The original text was written in Hebrew language.

[1] Fragments containing parts of this chapter were found among the Dead Sea Scrolls (3rd century BCE or later):[2] Extant ancient manuscripts of a translation into Koine Greek known as the Septuagint, made in the last few centuries BCE, include Codex Vaticanus (B;

[3] The parashah sections listed here are based on the Aleppo Codex.

There are varied translations of the opening words of this chapter: 2 Kings 3:4 states that: "Within three years" may refer to the attack of Sargon II "in 715 BC" to put down a rebellion in Moab.