Jeffersonville is a home rule-class city[5] in Montgomery County, Kentucky, in the United States.

Jeffersonville began as an important cattle-trading center in Eastern Kentucky during the mid-19th century.

It was then known as "Ticktown", either for the tickgrass (Eragrostis echinochloidea) in the area or for the ticks in the cattle pens.

Although it is unknown when the settlement became known as Jeffersonville, the first post office was established under that name on March 9, 1866.

19.6% of all households were made up of individuals, and 8.8% had someone living alone who was 65 years of age or older.

Most students residing within Jeffersonville attend the following schools, which are located in nearby Mount Sterling: