[20] He made a cameo appearance as himself, in the 2008 comedy You Don't Mess with the Zohan, and also in The Big Tease as the fictional John Paul Mitchell.

[24][25][26] The original Patrón Tequila was produced by Casa 7 Leguas, one of the oldest Mexican distilleries;[27] DeJoria and Martin Crowley purchased the brand rights in 1989 via their St. Maarten Spirits company.

[31][32][33] In addition to the mileage fees paid to Amtrak to transport the train car across the United States, it costs $10,000 a month to staff, maintain, store, and insure the Patrón Tequila Express.

[35] He also has three children from previous relationships, John Paul II (or Jr.),[36] Alexis Jones (with former wife Jamie Briggs),[37][38] and Michaeline.

[14] In 2008, DeJoria traveled to sub-Saharan Africa to join Nelson Mandela in his efforts to help feed over 17,000 orphaned children through Food4Africa.

[43] Dejoria is a co-creator of Grow Appalachia, an organization begun in 2009 which helps promote healthy food and teaching farming skills.

[47][48] In 2018, when DeJoria finalized the purchase of Taymouth Castle, he paid £10 million to his lawyer, Stephen Jones, for the transaction.

However, Jones absconded with the funds, leaving DeJoria and his fellow investors to pay for the property a second time.

This acquisition includes the Hamburger University training facility, in addition to the Hyatt-branded and managed hotel, The Hyatt Lodge.

[49] In 2022, he pledged £20,000 to save the 19th century frigate HMS Unicorn, one of the oldest surviving ships in the world.