From 1996 to 2020, he was a faculty member in the department of cellular molecular pharmacology at the University of California, San Francisco.
[1] He was a postdoctoral fellow at Yale University (1993–1996), where he worked with Arthur Horwich studying the mechanism of GroEL.
The team also develops experimental and analytical approaches for exploring the organizational principles of biological systems and globally monitoring protein translation through ribosome profiling.
A broad goal of his work is to bridge large-scale approaches and in depth mechanistic investigations to reveal the information encoded within genomes.
[4][5][6] Weissman has been a member of the National Academy of Sciences since 2009. in 2015, he co-founded the Innovative Genomics Institute with Jennifer Doudna.