Karditsomagoula (Greek: Καρδιτσομαγούλα) is a large village in the Karditsa regional unit in Greece, with nearly 2,000 inhabitants.

It is part of the municipality of Karditsa and is situated north of the central area of Karditsa, separated from it by the Greek National Road 30 (Arta - Trikala - Karditsa - Volos).

It is located southeast of Trikala, southeast of Larissa, west of Palamas, northwest of Sofades, and northeast of the Plastiras Dam.

Farmlands dominate the area around Karditsomagoula, the main product being cotton covering 26,000 acres (105 square kilometres) of land.

[citation needed] Other products include cattle, fruit and vegetables, and some flowers.