Khok Pho Chai (Thai: โคกโพธิ์ไชย, pronounced [kʰôːk pʰōː tɕʰāj]; Northeastern Thai: โคกโพธิ์ไชย, pronounced [kʰôːk pʰo᷇ː sa᷇j]) is a district (amphoe) of Khon Kaen province, northeastern Thailand.

The minor district (king amphoe) was established on 30 April 1994 by splitting it from Mancha Khiri district.

[3] Neighboring districts are (from the north clockwise): Mancha Khiri, Chonnabot, and Waeng Yai of Khon Kaen Province; Khon Sawan and Kaeng Khro of Chaiyaphum province.

The district is divided into four subdistricts (tambons), which are further subdivided into 40 villages (mubans).

The township (thesaban tambon) Ban Khok covers parts of tambon Ban Khok.