Nong Ruea (Thai: หนองเรือ, pronounced [nɔ̌ːŋ rɯ̄a]; Northeastern Thai: หนองเฮือ,[citation needed] pronounced [nɔ̌ːŋ hɯ̂a]) is a district (amphoe) of Khon Kaen province, northeastern Thailand.

Neighboring districts are (from the west clockwise): Chum Phae, Phu Wiang, Ubolratana, Ban Fang, and Mancha Khiri of Khon Kaen Province, and Ban Thaen of Chaiyaphum province.

The district is divided into 10 subdistricts (tambons), which are further subdivided into 149 villages (mubans).

There are three townships (thesaban tambons): Nong Ruea covers parts of tambons Nong Ruea and Nong Kae, parts of tambons Kut Kwang, Non Sa-at, and Dom Mong, and parts of Bang Kong and Chorakhe.

Two major factories can be found in the Nong Reua District: the Mitr Phu Viang sugar refinery, and the Khon Kaen Fishing Net Co. Ltd.