Phra Yuen (Thai: พระยืน, pronounced [pʰráʔ jɯ̄ːn], Northeastern Thai: พระยืน, pronounced [pʰàʔ jɯ̄ːn]) is a district (amphoe) of Khon Kaen province, northeastern Thailand.

The minor district (king amphoe) Phra Yuen was established on 18 October 1976 by splitting off the three tambons: Phra Yuen, Phra Bu, and Ban Ton from Mueang Khon Kaen district.

[2][3] Neighboring districts are (from the north clockwise): Ban Fang, Mueang Khon Kaen, Ban Haet and Mancha Khiri.

The district is divided into five subdistricts (tambons), which are further subdivided into 46 villages (mubans).

There are two townships (thesaban tambons): Ban Ton covers tambon Ban Ton, and Phra Yuen covers parts of tambon Phra Yuen.