Sam Sung (Thai: ซำสูง, pronounced [sām sǔːŋ]; Northeastern Thai: ซำสูง, pronounced [sa᷇m sǔːŋ]) is a district (amphoe) of Khon Kaen province, northeastern Thailand.

The minor district (king amphoe) was established on 31 March 1994 by splitting five tambons from Kranuan district.

The establishment of the new district became effective on 30 April.

[4] Neighboring districts are (from the southwest clockwise): Mueang Khon Kaen, Nam Phong, and Kranuan of Khon Kaen Province; Chuen Chom and Chiang Yuen of Maha Sarakham province.

The district is divided into five subdistricts (tambons), which are further subdivided into 34 villages (mubans).