Si Chomphu (Thai: สีชมพู, pronounced [sǐː tɕʰōm.pʰūː]; Northeastern Thai: สีชมพู, pronounced [sǐ sôm.pʰûː]) is a district (amphoe) of Khon Kaen province, northeastern Thailand.

The district was established as a minor district (king amphoe) on 1 July 1965, when three tambons, Si Suk, Si Chomphu, and Na Chan were split from Chum Phae district.

[2] Neighboring districts are (from the north clockwise): Si Bun Rueang of Nong Bua Lamphu province; Nong Na Kham, Wiang Kao, and Chum Phae of Khon Kaen Province; and Phu Kradueng of Loei province.

The district is divided into 10 subdistricts (tambons), which are further subdivided into 107 villages (mubans).

Si Chomphu is a township (thesaban tambon) and covers parts of tambon Wang Phoem.