[a] Silverbrook has founded companies and developed products in a wide range of disciplines, including computer graphics, video and audio production, scientific computing, factory automation, digital printing, liquid crystal displays (LCDs), molecular electronics, internet software, content management, genetic analysis, MEMS devices, security inks, photovoltaic solar cells, and interactive paper.

In 1985, Silverbrook founded Integrated Arts, a parallel processing and computer graphics company using the Inmos transputer.

In order to register so many ideas, Silverbrook started a company, Priority Matters, whose purpose was to file his patents.

[8][9] Silverbrook is Founder and Chairman of Australian company Geneasys (Genetic Analysis Systems), which is developing "KeyLab" a new class of medical diagnostic device which analyses multiple diseases from DNA using a standard smartphone.

The stated goal of Geneasys is "to equip medical professionals, primary care workers, aid workers, veterinarians, military personnel and private citizens with a simple to use, low cost, and highly accurate diagnostic devices".

Prototype printers were demonstrated at the Consumer Electronics Show (CES 2011),[15] and announced by such major companies as LG, Fuji Xerox, Canon, Toshiba, Lenovo, Océ and Medion.

[16][17] In March 2012, the George Kaiser Family Foundation (principal investor in Memjet) filed a lawsuit against Silverbrook and Silverbrook Research, alleging fraud and seeking to gain control of the Memjet patent portfolio, numbering over 4,000 patents.