Kleidonia (Greek: Κλειδωνιά) is a village and a community in the municipality of Konitsa, Ioannina regional unit, Epirus, Greece.

The community includes the village Kalyvia.

The Greek National Road 20 (Ioannina - Konitsa - Kozani) passes through Kalyvia.

It is situated on the right bank of the river Voidomatis, a tributary of the Aoos.

Two prehistoric locations have been found near Kleidonia: In these two caves there are archaeological remains that date back to 20,000 and 12,000 years ago, in the later period of the Paleolithic Era in Greece.