In 2013, a remake of the Japanese live TV series, called Mischievous Kiss: Love in Tokyo, was made.

In an interview, the author's widower, Shigeru Nishikawa, revealed that the manga's intended finale was to be conceptualized in the anime for the first time.

Naoki eventually falls for Kotoko despite her clingy ways and childish behavior and starts to have romantic, protective feelings for her.

In 1996, Itazura na Kiss was first adapted into a Japanese television drama of the same title, which ran from October 14 to December 16, 1996, for 9 episodes every Monday at 20:00 until 21:00 JST.

In 2010, it was adapted into a South Korean drama series, Playful Kiss, starring Kim Hyun-joong of SS501 as the perfectionist Baek Seung-jo and Jung So-min as the clumsy Oh Ha-ni.

[11] In 2013, a second Japanese live-action adaptation aired on Fuji TV under the title Mischievous Kiss: Love in Tokyo.

[12] In 2016, it was adapted into a second Taiwanese drama, Miss in Kiss, starring Esther Wu as Xiang Yue-qin and Dino Lee as Jiang Zhi-shu.

[14] Itazura na Kiss was adapted into a 25 episode Japanese animated TV series by TMS Entertainment and shown on TBS from April 4, 2008 to September 25, 2008.