A six-time All-Star, he was named to the All-NBA Third Team in 2016 and won an NBA championship with the Toronto Raptors in 2019, their first and only title in franchise history.

He is widely regarded as one of the greatest Raptors players of all time due to his work with turning the franchise around, from the post-Vince Carter era to their first-ever championship in 2019.

Lowry played two seasons of college basketball with the Villanova Wildcats before he was selected by the Memphis Grizzlies in the first round of the 2006 NBA draft with the 24th overall pick.

[15] The 2008–09 season saw Lowry and good friend Mike Conley Jr. compete for playing time and the starting point guard position.

[34] Despite the trade, which was meant to help the struggling Raptors return to relevance, the team finished the season with a 34–48 record, missing the playoffs.

Ujiri believed that Lowry had the potential to be a star, but found that his reputation around the NBA had more to do with his history of clashing with coaches and his body language than his talent.

[16] The post-Gay Raptors quickly emerged as one of the best teams in the Eastern Conference, and many cited Lowry's strong play and leadership as a significant factor in their success.

They made the playoffs for the first time since 2008, but lost in the first round to the Brooklyn Nets after Lowry's potential game-winning shot was blocked by Paul Pierce in Game 7.

Lowry entered the off-season as one of the NBA's most coveted free agents, attracting interest from the Miami Heat, Houston Rockets, and other teams.

[40] On January 5, 2015, Lowry was named the Eastern Conference Player of the Month for December 2014, making him only the second Raptor, after Chris Bosh, to receive this recognition.

[43] Lowry finished the All-Star game with 10 points, a team-high eight assists, three rebounds and four steals in a loss to the West, completing his first in-game dunk since 2009.

[45] The Raptors finished the 2014–15 season with a franchise-best 49–33 record, fourth in the East and first in the Atlantic, but were swept in the first round by the Washington Wizards, despite entering the series with homecourt advantage.

[46] Following his disappointing performance in the playoffs, Lowry entered the 2015–16 season with a noticeably slimmer physique, looking "as trim and fit as he ever has during his nearly decade-long NBA career", according to Toronto Sun writer, Ryan Wolstat.

"[48] On November 3, he scored a game-high 27 points against the Dallas Mavericks as the Raptors started 4–0 for the first time in franchise history (the streak eventually ended with five wins).

[50] On January 18, 2016, Lowry tied his career-high of made three-pointers in game with seven, scoring a game-high 31 points in total, in a 112–100 win over the Brooklyn Nets.

[54] The following day, Lowry and teammate DeMar DeRozan were selected as co-winners for Eastern Conference Player of the Month for January.

[55] On February 14, Lowry finished his second All-Star game, held in Toronto for the first time, with 14 points, 10 assists, 5 rebounds, and 2 steals in the East's 196–173 loss to the West.

On February 22, he recorded his eighth career triple-double (sixth as a Raptor) with 22 points, 11 assists and 11 rebounds in a 122–95 win over the New York Knicks.

Lowry entered the playoffs suffering from bursitis in his shooting elbow, as he shot a mere 32% from the field over the final 10 games of the regular season.

[64] In Game 7 of the series, he scored 35 points on 11-of-20 shooting, to go along with nine assists, seven rebounds, and four steals, in a 116–89 win, helping the Raptors advance to the Eastern Conference Finals for the first time in franchise history.

[65] In Game 4 of the Conference Finals against the Cleveland Cavaliers, Lowry scored 35 points on 14-of-20 shooting to help the Raptors win 105–99 and tie the series at 2–2.

With his first selection to the All-NBA team, he joined Vince Carter and Chris Bosh as the only players in franchise history to receive this recognition.

[71] He set a new season high on December 23, scoring 36 points, including 19 in the fourth quarter, to lead the Raptors to a 104–98 victory over the Utah Jazz.

[77] On April 5, 2017, he returned from an 18-game absence with a wrist injury, played 42 minutes, and had 27 points and 10 assists to help the Raptors overcome a 20-point first-half deficit in a 105–102 victory over the Detroit Pistons.

[81][82] On October 27, 2017, he recorded his first triple-double of the season and his eighth as a Raptor with 11 points, 12 assists, and 10 rebounds in a 101–92 win over the Los Angeles Lakers.

[120] On May 2, 2021, Lowry scored a new season-high 37 points and made a career-high tying eight three-pointers with two rebounds, 11 assists and a steal in a 121–114 win against the Los Angeles Lakers.

[121] On August 6, 2021, the Miami Heat acquired Lowry from the Raptors via a sign-and-trade in exchange for former teammate Goran Dragić and Precious Achiuwa.

[128] On April 11, 2023, during the Heat's play-in tournament game against the Atlanta Hawks, Lowry scored a season-high 33 points, alongside four rebounds and five assists, in a 116–105 loss.

[131] On January 23, 2024, Lowry was traded to the Charlotte Hornets, alongside a first-round draft pick, in exchange for Terry Rozier.

"[16] In 2014, Zach Lowe of Grantland wrote that Lowry "was probably the best point guard in the Eastern Conference from start to finish [of the 2013–14 season], raining off-the-bounce 3s, getting Toronto into its offense, toning down the wild gambles on defense, and using that stubby little body to draw more charges than anyone.