[5][6] Leucine-rich repeat-containing protein 50 is cilium-specific and is required for the stability of the ciliary architecture.

It is involved in the regulation of microtubule-based cilia and actin-based brush border microvilli.

[5] Mutations in the LRRC50 gene are associated with primary ciliary dyskinesia.

[6] This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 16 is a stub.