Radial spoke

The radial spoke is a multi-unit protein structure found in the axonemes of eukaryotic cilia and flagella.

[1] Although experiments have determined the importance of the radial spoke in the proper function of these organelles, its structure and mode of action remain poorly understood.

Radial spokes are T-shaped structures present inside the axoneme.

Each spoke consists of a "head" and a "stalk," while each of these sub-structures is itself made up of many protein subunits.

For example, mutant organisms lacking properly functioning radial spokes have flagella and cilia that are immotile.

The radial spoke shown in an axoneme cross-section