LaCrosse is a town in Alachua County, Florida, 15 miles (24 km) north of Gainesville.

The LaCrosse is part of the Gainesville, Florida Metropolitan Statistical Area.

The climate in this area is characterized by hot, humid summers and generally mild winters.

As of the 2020 United States census, there were 316 people, 108 households, and 86 families residing in the town.

[12] As of the 2010 United States census, there were 360 people, 124 households, and 105 families residing in the town.

[14] The Alachua County Library District serves LaCrosse with a weekly bookmobile stop.