Leopold Bros distills over twenty hand-numbered, small-batch products, all made from scratch and natural ingredients, which are distributed in over twenty states, the District of Columbia, and parts of Europe.

[2][3][4][5] Brothers Scott and Todd Leopold, opened a brewpub on South Main Street at the site of a renovated brake factory in Ann Arbor, Michigan in 1999.

Scott Leopold, an environmental engineer, was crucial in the design stages attempting to create as near a zero-pollution factory as possible.

[6] The microbrewery operated as an "eco-brewery" using organic hops and barley, and used equipment and procedures designed to reduce wastewater and other waste by-products in the beer-making process.

[7][8] Leopold Bros. closed its Ann Arbor location in the Spring of 2008, relocating to Denver, where it discontinued brewing and began operating as a micro-distillery alone.