Located immediately to the north of Bucknell University, and dating to 1848, it is a contributing site of the Lewisburg Historic District.

Upon completion of the cemetery's boundaries of its original 6 acres (2.4 ha), interments from other graveyards in the town, and from Crossroads Church in nearby Buffalo Township, were moved here.

[1] The McClure Monument, dating to around 1833, was removed to the cemetery from the graveyard of the Presbyterian Church on Market Street (Pennsylvania Route 45).

[3] The original cemetery is located off to the right, well beyond the end of the paved Chapel Lane, once inside the main gate.

[2] Inside the gate there formerly stood a two-story arched gatehouse, where the cemetery's sexton lived.

[4] Many of the cemetery's headstones were carved, in Quincy granite, by stonemason Chauncey Foster, including that of his wife, Enna, who died in 1908.