Lewisburg's street layout was designed by Ludwig Derr in 1785, and is believed to have been inspired by that of Philadelphia.

[1] As well as passing through downtown Lewisburg, 7th Street bisects the heart of the Bucknell University campus.

Entering downtown Lewisburg, it forms the southwestern boundary of Green Park, beside which it crosses Bull Run.

Three blocks later, at ROTC Drive, South 7th Street enters the campus of Bucknell University.

The headquarters of the university's student newspaper, The Bucknellian, are located in Stuck House on South 7th Street.