Lindgren oxidation

The oxidation takes place in water containing solvent mixtures under slightly acidic conditions (pH 3–5) with sodium chlorite as oxidizer.

In the original publication, sulfamic acid and resorcinol were used.

[1] George A. Kraus and co-workers were the first to use 2-methyl-2-butene as scavenger under buffered conditions for the oxidation of an aliphatic and an α,β-unsaturated aldehyde.

[2][3] Later hydrogen peroxide also proved to work to remove the hypochlorite.

This chemical reaction article is a stub.