[7] Wixson was born in Wichita, Kansas on April 11, 1994, to Thomas, who works installing satellite dishes, and Michele, a school bus driver.

[5] Around the same time, she was inspired by an article in the Reader's Digest about Bill Gates and other millionaires, stating that "it was talking about how they took the chance and they took their opportunities and they took it to a whole other level".

By September, W editor Stefano Tonchi ran a full-page close-up of her lips and the gap in her teeth, her two most arresting features, in his first issue of W magazine.

A press release about the campaign called her the "embodiment of a free-spirit on the cusp of womanhood" (she would stay with the brand for a two-season run).

[7] Her agent, Cheri Bowen at Marilyn Agency, said that Wixson is more interested in quality than quantity, "She's incredibly intelligent about the business.

[7] Wixson made her national television appearance on CNN, being introduced a "teen supermodel" at 17, as the cameras and reporter Alina Cho followed her home to Wichita to film her prom experience.

[24] In January of the same year she was also featured in the psychedelic band Animal Collective's video for their song Applesauce from Centipede Hz.

During the 2014 Paris Fashion Week, she modelled for Elie Saab and Atelier Versace, and for the Chanel Haute Couture show in Salzburg.

That season, she walked for designers including Chanel, Fendi, Roland Mouret, Michael Kors, Vera Wang, Balmain, Diane von Fürstenberg, Max Mara and Tom Ford.

Wixson began 2017 fronting a campaign for Dior, walking the Spring 2017 Chanel Haute Couture Show as well as appearing on the cover of Mexican Harper's Bazaar.

"[25][26] Wixson had suffered a foot injury that required her to refrain from continuing her modeling career, and decided to focus on "designing interiors, pottery, sculpting, carving, and inventing for the future.