[3] The region is comparable in size to the combined land area of the nation state of El Salvador.

Mara Region is known for being the home of Serengeti National Park, a UNESCO World Heritage site and also the birth place of Tanzania's founding father Julius Nyerere.

The most prevalent landscape seen in the natural vegetation is the “savannah type” most commonly found in areas that receive annual rainfall between 900 and 1200 mms/year.

The lowland zones with less annual rainfall consist of wooded grassland and bushland of dense thickets.

[8] 14,750 sq kilometers of land is occupied by the Serengeti National Park and is located at the border of the Arusha and Mara Region.

[8] Mining, fishing, tourism, cattle raising, crop farming, and cross-border operations are the mainstays of the Mara Region's distinctive and alluring economy.

Cassava, rice, maize, sorghum, finger-millet, bulrush millet, sweet potatoes, potatoes, beans, Bambara nuts, ground nuts, green gram, chickpeas, banana, cotton, coffee, sunflower, sesame, onions, tomatoes, watermelon, oranges, avocados, pawpaw, pineapples, and lemons are some of the crops grown in the area.

Along Lake Victoria, the Mara River, and its streams, fishing is done, with the activity rated as one of the region's top economic objectives.

[7] The most common methods of processing sardines in the area include sun drying, frying, and, in rare instances, smoking.

A monthly average catch of 3,452.25 metric tonnes is thought to be marketed both inside and beyond the Mara Region.

[7] Nile perch is a valuable source of food and nourishment for families, as well as a raw material for fish processing factories.

Musoma Fish Processors do processing in the area in the beaches of Ryamakabe, Toa, Ngonche, Msasani, and Bugambwa.

Listed as a World Heritage Site, the national park occupies a large area of grasslands and woodlands and is home to a diverse range of wildlife.

Additionally, Mara is also home to The Mwalimu Nyerere Museum, which houses historical facts on the country's independence.

The museum is situated in Butiama Village, the final resting place of Mwalimu Julius Kambarage Nyerere, the country's founding father.

[10][7] The Mara Region is the ancestral homeland to the following people groups:Zanaki, Luo, Kurya, Ngurimi, Ikoma, Ikizu, Kwaya, Jita, Suba, Kerewe, Sizaki and Simbiti.