It can be classified as lymphocytic, epithelial, or spindle cell histologies, but the clinical significance of these classifications is controversial.
[4] Tonofibrils seen under electron microscopy can differentiate thymoma from other tumors such as carcinoid, Hodgkin's, and seminoma.
Patients are usually asymptomatic but can present with myasthenia gravis-related symptoms, substernal pain, dyspnea, or cough.
Invasive tumors can produce compression effects such as superior vena cava syndrome.
For those with invasive thymoma, treatment is based on induction chemotherapy, surgical resection, and post-surgical radiation.
Hodgkin's lymphoma usually present in 40–50's with nodular sclerosing type (7), and non-Hodgkin's appears in all age groups.
A large minority of patients with a mediastinal teratoma (including dermoid cyst) will cough up hair.