The episode was written by Maurissa Tancharoen, Jed Whedon and Andrew Chambliss and directed by Dwight Little.
Boyd cannot find a trace of Echo and believes she has is no longer in the D.C. area and is hitch hiking her way around.
A manager tells her to move along, but Echo notices someone taking money from an ATM.
The clerk tells her they don't accept food stamps and she is forced to leave.
Galena is caught and Echo herself is cornered, but she is able to knock out the deputy after recalling an imprint and gets away.
She goes to the county jail to cover a sick nurse and give flu shots.
Back in the Dollhouse, Sierra and Victor have been imprinted with scientific backgrounds and seem to be developing something.
She notes that her imprint overcame her but then pulled back, but left remnants of it, allowing her to form her new persona.
After completing the presentation Harding notices Sierra and Victor grouping and plans to split them up.
He confides in Adelle that he believes Rossum's end game is to be able to imprint anyone without the use of Active architecture.
Adelle, however, betrays Topher and gives the technology to Rossum and regains control of the Dollhouse.
Rachel Reitsleff from iF Magazine said "Meet Jane Doe" was raising "the stakes and moves the arc forward efficiently, but sometimes it’s more expository than engrossing.
"[1] Eric Goldman from IGN said that the episode "served as a reminder that Dollhouse might have been better off if it had been approached from a very different, less Echo-centric overall dynamic from the start.