Methanofuran

Methanofurans (MFRs) are a family of chemical compounds found in methanogenic archaea.

[1] These species feature a 2-aminomethylfuran linked to phenoxy group.

Methanofuran converts to formylmethanofuran in an early stage of methanogenesis.

The enzyme formylmethanofuran dehydrogenase (EC: 1.2.99.5) formylates methanofuran using CO2, the primary C1 source in methanogenesis.

[2] The enzyme formylmethanofuran:tetrahydromethanopterin formyltransferase catalyzes the transfer of the formyl group from formylmethanofuran to N5 on tetrahydromethanopterin, H4MPT.