After the Battle of Sekigahara, Tokugawa Ieyasu assigned a 19,000 koku holding in this area to Hineno Yoshiaki, formerly of Takashima Domain in Shinano Province in 1602.
Hineno was instrumental in the construction of the Nikkō Tōshō-gū complex, and was rewarded for his efforts in 1634 by a transfer to Funai Domain (20,000 koku).
After his son, Katō Yoshinori was transferred to Minakuchi Domain in 1712, Mibu came under the control of the Torii clan, who then ruled until the Meiji Restoration.
The 6th daimyō, Torii Tadatomi, sided with the Satchō Alliance in the Boshin War of the Meiji Restoration, and fought in the Battle of Aizu, despite considerable opposition within the ranks of his samurai.
The final daimyō, Torii Tadafumi was later raised to the rank of viscount in the kazoku peerage system, and served as the Japanese consul to the Kingdom of Hawaii.