Maddux played in MLB from 1986 through 2000 for the Philadelphia Phillies, Los Angeles Dodgers, San Diego Padres, New York Mets, Pittsburgh Pirates, Boston Red Sox, Seattle Mariners, Montreal Expos, and Houston Astros.

Maddux has served as pitching coach for the Milwaukee Brewers, Texas Rangers, Washington Nationals, and St. Louis Cardinals.

The family moved to Taiwan when Mike was a toddler, and also spent time living in San Angelo, Texas, North Dakota, California, Madrid, Indiana, and eventually Las Vegas, Nevada.

[1] Beginning at the age of ten, Maddux received instruction in pitching from former Major League Baseball scout Ralph Meder.

Granted free agency after the 1990 season, he contacted each team in seeking a tryout, which resulted in the San Diego Padres signing him.

[6][7] After the 1992 season, the Padres traded Maddux to the New York Mets for Roger Mason and Mike Freitas.

After he retired as a player, Maddux became a pitching coach in Minor League Baseball for the Houston Astros organization, first with the Round Rock Express.

Beginning in 2003, Maddux spent six seasons as the pitching coach for the major league Milwaukee Brewers.

[14] After his first season as pitching coach with Texas, the club's ERA dropped nearly one full run (0.99).

The rotation was composed primarily of C. J. Wilson, with a 6.02 ERA when Maddux arrived; Colby Lewis, who had just pitched in Nippon Professional Baseball in Japan; Scott Feldman, and Tommy Hunter.

[14] During Maddux's time with the Rangers, the club won 612 games, third-most in the AL, and achieved a collective ERA of 4.04, including four consecutive seasons below 4.00.

[14] Five pitchers became All-Stars in Maddux's tenure: Yu Darvish, Neftalí Feliz, Matt Harrison, Alexi Ogando, and Wilson.

[16] During the 2011 offseason, the Cubs fired Mike Quade as their manager and considered Maddux as a potential replacement.

[22] The Washington Nationals signed Maddux with a two-year contract to become their pitching coach on November 4, 2015.