The company primarily designed memory chips and were especially known for their Multibank DRAM and 1T-SRAM technologies—the latter used on Nintendo's Wii and GameCube video game consoles.

The initial design team staffed engineers poached from Integrated Device Technology, ISSI, Rambus, and Plus Logic.

[3] The company's first major product was a specialized type of dynamic random-access memory that Monolithic termed Multibank DRAM (MDRAM).

[4] MDRAM secured design wins in July 1994 with Tseng Labs, Trident Microsystems, and S3 Inc. using the chips in their graphics accelerator cards.

[5] MDRAM required a proprietary interface and could not be adapted to the SIMM card standard for desktop computer memory of its day.

[9] The academics Bruce Jacob, Spencer W. Ng, David T. Wang, writing in the book Memory Systems (2008), called the name a misnomer: "[1-transistor static RAM] is not really possible, but it makes for a catchy name".

[16] The Wall Street Journal saw this as a rekindling of interest in technology companies in the stock market, which had fallen in the twilight of the dot-com bubble.

In late December 2004, following ill-health and a tough year for the company, chairman Fu-Chieh resigned from Monolithic, with chief financial officer Mark Voll taking the mantle.