Molsidomine (trade names Corvasal, Corvaton and many others) is an orally active, short acting vasodilating drug used to treat angina pectoris.

[1] Molsidomine is used for the prevention and long-term treatment of stable and unstable angina pectoris, with or without left heart failure.

[2][3] The drug must not be used in patients with acute cardiac arrest or severe hypotension (low blood pressure), during lactation, and in combination with PDE5 inhibitors such as sildenafil.

Side effects occurring in fewer than 1% of patients include dizziness, nausea, reflex tachycardia (fast heartbeat), hypersensitivity reactions, as well as thrombocytopenia (low blood platelet count) in rare cases.

It releases NO, which acts as a gaseous signaling molecule, relaxing the smooth muscles of blood vessels.

[2][4] Molsidomine and linsidomine are sydnone imines, a class of mesoionic heterocyclic aromatic chemical compounds.