Natrona is an unincorporated community in Pratt County, Kansas, United States.

[1] It is located six miles northeast of Pratt along NE 40th Ave on the north side of Highway 61.

German-speaking Lutheran settlers hailing from Saxony began settling in northeastern Pratt County in the 1870s, moving south from around Ellsworth after their crops were eaten by birds.

[3] The town had a population of 25 in 1910 and is located along the Chicago, Rock Island, and Pacific Railroad.

[5][4] The community is served by Pratt USD 382 public school district.