Neutrophil cytosolic factor 1

1GD5, 1K4U, 1KQ6, 1NG2, 1O7K, 1OV3, 1UEC, 1W70, 1WLP65336117969ENSG00000158517ENSMUSG00000015950P14598Q09014NM_000265NM_001286037NM_010876NP_000256NP_001272966NP_035006Neutrophil cytosol factor 1, also known as p47phox, is a protein that in humans is encoded by the NCF1 gene.

[5] The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase.

This oxidase is a multicomponent enzyme that is activated to produce superoxide anion.

[5] Genetic variability in the NCF1 gene has been found to be related to a higher chance of getting autoimmune diseases such as Sjögren's syndrome, rheumatoid arthritis and lupus erythematosus.

[6] Neutrophil cytosolic factor 1 has been shown to interact with: