Neutrophil cytosolic factor 2

1E96, 1HH8, 1K4U, 1OEY, 1WM5, 2DMO468817970ENSG00000116701ENSMUSG00000026480P19878O70145NM_000433NM_001127651NM_001190789NM_001190794NM_010877NP_000424NP_001121123NP_001177718NP_001177723NP_035007Neutrophil cytosol factor 2 is a protein that in humans is encoded by the NCF2 gene.

This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein complex known as NADPH oxidase found in neutrophils.

This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome.

Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease.

This article on a gene on human chromosome 1 is a stub.