The portion of current Route 50 between Seaville and Petersburg received funding in 1910 to become a spur of the Ocean Highway.

Route 50 begins at an intersection with US 9 in the Seaville section of Upper Township, Cape May County, heading to the north on a two-lane undivided road.

Upon leaving Petersburg, Route 50 turns to the north again and crosses over the Beesleys Point Secondary, intersecting CR 631.

[1][2] CR 557 splits from Route 50 by heading northwest on Buena Tuckahoe Road and Route 50 heads through some agricultural clearings concurrent with CR 557 Truck, passing to the west of the MacNamara Wildlife Area, which is known as a breeding ground for several species of birds.

[2][4] The route crosses the South River into Weymouth Township, passing the residential community of Belcoville to the east and meeting CR 669.

[1][2] It soon enters Hamilton Township, where the name of the road becomes Mill Street and it comes to a junction with US 40 (Harding Highway).

[1][2] US 40 and Route 50 follow the Harding Highway, a two-lane undivided road, turning to the northeast and crossing the Great Egg Harbor River.

The route turns to the northeast, passing near the Clover Leaf Lakes residential development, before coming to a diamond interchange with US 322 (Black Horse Pike).

The route becomes a two-lane undivided road again and continues through inhabited areas, crossing into Galloway Township, where there is an intersection with CR 686.

[7] The portion of current Route 50 between Seaville and Petersburg received funding to become a spur of the Ocean Highway in 1910.

As part of the project, the current northbound exit on the left-side of the parkway would be rebuilt on the right hand side.