In 1878/79, the Horchheim rail bridge was opened to the south of Koblenz to connect the east and west Rhine lines.

After the Niederlahnstein–Hohenrhein section of the Lahn Valley Railway was destroyed in the Second World War it was rebuilt as a single-track line.

During the introduction of the interim Rhineland-Palatinate integrated regular-interval timetable (Rheinland-Pfalz-Taktes) between early June 2004 and early November 2009, Niederlahnstein station was made a pilot project of Rhineland-Palatinate to convert it into an "environmental station".

In the summer of 2008, the second phase of the project was completed and the Oberlahnstein–Niederlahnstein section was connected to the electronic interlocking system.

As a result, VIAS GmbH took over operations between Neuwied, Koblenz, Wiesbaden and Frankfurt under the 2010/2011 timetable on 12 December 2010.

All local trains (Regional-Express and Regionalbahn) running on the two lines serving the station stop here.

The southern section of the East Rhine Railway (Koblenz–Wiesbaden–Frankfurt) was served until the beginning of the 2010/2011 timetable in December 2010 by the Loreley-Bahn (RB 10) and the Loreley-Express (RE 10), which were operated by Deutsche Bahn (DB).

Both these services have been operated by DB Regio Südwest and marketed as the Lahn-Eifel-Bahn since the timetable change in December 2014.