Nitrotyrosine is identified as an indicator or marker of cell damage, inflammation as well as NO (nitric oxide) production.

It is detected in large number of pathological conditions[3][4] and is considered a marker of NO-dependent, reactive nitrogen species-induced nitrative stress.

Increased level of nitrotyrosine is detected in rheumatoid arthritis,[5] septic shock[6] and coeliac disease.

[4][9] Research shows that nitrotyrosine levels can be reduced by N-acetyl cysteine,[10][11] which is a precursor to glutathione, one of the body's primary endogenous antioxidants.

[15] Tyrosine is the precursor to dopamine, a neurotransmitter that's important for motivation, attention, learning, circadian rhythms, and other biological processes.