Octadecyltrimethoxysilane (OTMS) is an organosilicon compound.
This colorless liquid is used for preparing hydrophobic coatings and self-assembled monolayers.
It is sensitive toward water, irreversibly degrading to a siloxane polymer.
[2] It places a C18H39SiO3 "cap" on oxide surfaces.
The formation of OTMS monolayers is used for converting hydrophilic surfaces to hydrophobic surfaces, e.g. for use in certain areas of nanotechnology and analytical chemistry.