[2] Azure magazine wrote, "Odeyto pays more than lip service to the implementation of Native building practices, giving gorgeous physical form to an important – and long-neglected – aesthetic.

[6] Odeyto Indigenous Centre was a joint effort of the Truth and Reconciliation Commission of Canada, Seneca College, and the provincial government.

[7][6] The college's purpose-built Odeyto allows these students to feel valued, engage and bond with the Seneca community, and reclaim their space by celebrating Indigenous culture.

[6][2] Brian Porter and Matthew Hickey of Two Row Architect came up with a design concept inspired by an upturned, resting canoe, symbolizing the students' stop at Seneca College to gather knowledge before continuing on life's journey.

[2][6] Odeyto Indigenous Centre's exterior is clad with triangular zinc shingles that are folded and interlocked to replicate the White Pine Tree of Peace, a symbol of the Haudenosaunee wampum belt.

[6] In addition, the building is decorated with contemporary art by Kent Monkman and Steven Paul Judd, both Indigenous Canadian artists.

[7] The kitchen has fluted ceramic tiles that relate to the nearby artwork, "Dish with One Spoon wampum land acknowledgment belt.

[2] In June each year, the building's primary circulation axis aligns with the summer solstice, a time when many Indigenous people celebrate traditional sunrise ceremonies.