The southern terminus of State Route 682 is at a trumpet interchange with US 33, US 50 and SR 32 in Athens.

Its northern terminus is at SR 13 in the village of Chauncey, Ohio.

The entirety of SR 682 is located in the central part of Athens County.

It is not a component of the National Highway System, a system of highways deemed most important for the economy, mobility and defence of the nation.

A re-routing of US 33 out of Chauncey and onto this new expressway resulted in an extension of SR 682 northeasterly into the village along the former two-lane routing of US 33 up to the state highway's current northern terminus at the SR 13 junction (the remainder of the old 33 became an extension for SR 13).