[1]: 1368  A synthetic nitroimidazole, it is commercially obtained from an acid-catalyzed reaction between 2-methyl-5-nitroimidazole and epichlorohydrin.

Antimicrobial spectrum is similar to that of metronidazole and is more well tolerated;[1]: 1368  however there are concerns of lower relative efficacy.

[3] It was first introduced for treating trichomoniasis before being recognized for its broad anti-protozoan and anti-anaerobic-bacterial capacities.

[4]: 1261  has also been investigated for use in Crohn's disease after bowel resection.

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