[3] The OHP assay measures the integrated effect of procoagulant, anticoagulant, and fibrinolytic factors.
[1] The test is potentially useful in the evaluation of hypercoagulability, hypocoagulability, and fibrinolytic abnormalities.
[3][4] The test has also been used to study coagulation in feminizing hormone therapy in transgender women.
[5] However, more studies are needed to validate the test as a biomarker of thrombosis and other abnormalities of coagulation.
[1] Since then, a modified version has been developed which can use either thrombin or tissue factor to trigger coagulation.