The two-way roadway is 4.8 kilometers long, starts at PR-2 in Barrio San Antón and runs westward.

The road is named "Avenida Julio Enrique Monagas" from kilometer 0.0 at PR-2, in the western end of Barrio San Antón, to kilometer 0.7 in central Barrio San Antón, where it then starts to run over Avenida Las Américas.

It then runs its next 4.1 kilometers over Avenida Las Américas until its western terminus at its junction with PR-500 in Barrio Canas.

Continuing west from PR-12, the road crosses over Río Portugués before passing by Hospital Metropolitano Dr. Pila.

The less transited western section of this road experiences an hourly traffic flow upwards of 2400 vehicles.