Paget–Schroetter disease (which evolved from a venous thoracic outlet syndrome) is a form of upper extremity deep vein thrombosis (DVT), a medical condition in which blood clots form in the deep veins of the arms.

[4] Paget–Schroetter syndrome was described once for a viola player who suddenly increased practice time 10-fold, creating enough repetitive pressure against the brachiocephalic and external jugular veins to cause thrombosis.

[6] Symptoms may include sudden onset of pain, warmth, redness, blueness and swelling in the arm.

[9] The traditional treatment for thrombosis is the same as for a lower extremity DVT, and involves systemic anticoagulation to prevent a pulmonary embolus.

[11] If there is thoracic outlet syndrome or other anatomical cause then surgery can be considered to correct the underlying defect.