Pancreatic polypeptide cells

The pancreatic islets, where PP cells reside, was discovered in 1869 by a German pathological anatomist and scientist, Paul Langerhans.

Pancreatic polypeptide also works to regulate glycogen levels and the amount of secreted substances from gastrointestinal cells and tissue.

[citation needed] Once it is produced, pancreatic polypeptide is shown to be a 36 amino acid long peptide that can be sent out to different areas within the pancreas or organism.

[1] Given that PP cells reside in the pancreas and serve both the digestive and endocrine systems, the roles it can play within a clinical setting are vast and important to analyze.

Many of the applications geared around pancreatic polypeptide cells and the substances they secrete serve to better understand and treat diabetes better than it already is, and they have been heavily studied in rats.

Studies are also being pursued to see how PP cells and the substances they release can help individuals who do not have a pancreas anymore due to various circumstances regulate insulin levels and maintain homeostasis.

[3] Another area of clinical research surrounding the pancreatic islets and PP cells is in regards to cellular communication.

[1] The current studies being done mainly focus on diabetes and preventing the adverse effects it poses on mammalian organisms.