Penn State Health Holy Spirit Medical Center[1] is a 307-bed non-profit Catholic community hospital located in Camp Hill, Pennsylvania, a suburb of Harrisburg, Pennsylvania, and serves as the primary facility for its related health system.

[5] Holy Spirit is a Level III Neonatal intensive-care unit.

[2] Physician residency programs, affiliated with Memorial Hospital in York, Pennsylvania, exist on-site for emergency medicine and surgery.

[6] On September 9, 2013, Holy Spirit Health System signed a letter of intent with Geisinger Health System,[7] On September 1, 2017, Geisinger Holy Spirit was granted Level II Trauma Center accreditation by the Pennsylvania Trauma Systems Foundation.

[9] On November 1, 2020, Holy Spirit was acquired by Penn State Health, including its medical group and ambulance service.